Anti-NDRG2 Antibody
ABI-NDRG2-0020 100 µL
Synonyms: SYLD, KIAA1248, N-Myc Downstream-Regulated Gene 2 Protein, N-Myc Downstream Regulator 2, NDR1-Related Protein NDR2, Cytoplasmic Protein Ndr1, Syld709613 Protein
Data Sheet: 
Reactivity
Human, Mouse, and Rat
Applications
ICC, IHC, WB
Concentration
200 µg/mL
Shipment
Ice packs
Long Term Storage
Store at 4°C in the dark. Under these conditions, the antibodies should have a shelf life of at least twelve months, provided they remain sterile. For longer term storage, aliquot and freeze to avoid freeze-thaw of the antibody.
Shelf Life
12 months from receipt of product
Description
Our Anti-NDRG2 chicken polyclonal primary antibody from Aves Labs is produced in-house. It detects human, mouse, and rat NDRG2, and is affinity-purified IgY. It is great for use in IHC, ICC, WB. - NDRG2, or N-myc downstream-regulated gene 2, is a downstream target of the N-myc proto-oncogene. NDRG2 was initially identified for its role in cell differentiation and response to cellular stress. Multiple studies have determined that NDRG2 mRNA is downregulated or undetectable in several human cancers, and over-expression of NDRG2 inhibited the proliferation of cancer cells. Commonly regarded as a tumor suppressor, NDRG2 also plays a crucial role in regulating cell proliferation, apoptosis, and metastasis. In neuroscience, studies of astrocytes in the central nervous system have implicated NDRG2 in the pathogenesis of many neurological diseases not limited to tumors; including stroke, neurodegenerative diseases, and psychiatric disorders. Its involvement in maintaining the integrity of the blood-brain barrier adds to its significance in neurobiology (Takarada-Iemata et al. Glia, 2018). Drug therapies to modulate the expression of NDGR2 may be able to help patients suffering from disease states ranging from multiple cancer types to Alzheimer’s, Parkinson’s, and depression. -
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
