Anti-Kv3.1B K+ Channel Antibody FL490 Conjugate

  ABI-75-041-FL490 200 µL

Data Sheet:    

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Hamster, Human, Non-Human Primate, Mouse, and Rat  

IHC, ICC  

N16B/8  

0.5 mg/mL  

Shipped on ice packs  

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.  

12 months from date of receipt  

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Description

 

Our Anti-Kv3.1b K+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N16B/8. It detects hamster, human, non-human primate, mouse, and rat Kv3.1b K+ channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC. - Potassium voltage-gated channel subfamily C member 1, or Kv3.1b is encoded by the gene KCNC1. Kv3.1 is a member of the Shaw subfamily of voltage gated potassium channels. Kv3.1b is expressed in many parts of the brain including the cerebellum, globus pallidus, subthalamic nucleus, substantia nigra, cortical and hippocampal in neurons at presynaptic membranes. It is also expressed in retinal ganglion cells and muscle and testis tissues. It is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. Its function is important in repolarization of action potentials and is expressed in neurons that execute repetitive high frequency firing. Alterations in expression are associated with certain types of epilepsy, spinocerebellar ataxia, unverricht-lundborg syndrome and demyelinating diseases. -

 

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