Anti-Kv2.2 Potassium Channel Antibody

  ABI-75-358 100 µL

Data Sheet:    

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Mouse and Rat  

WB, IHC, ICC, ELISA  

N372C/51  

1 mg/mL  

Shipped on ice packs  

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.  

24 months from date of receipt  

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Description

 

Our Anti-Kv2.2 potassium channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N372C/51. It is KO validated, detects mouse and rat Kv2.2 potassium channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB. - Voltage-gated K+ channels are important determinants of neuronal membrane excitability (Pongs, 1999). Moreover, differences in K+ channel expression patterns and densities contribute to the variations in action potential waveforms and repetitive firing patterns evident in different neuronal cell types. The delayed rectifier-type (IK)channels (Kv1.5, Kv2.1, and Kv2.2) are expressed on all neuronal somata and proximal dendrites and are also found in a wide variety of non-neuronal cells types including pancreatic islets, alveolar cells and cardiac myocytes (Hwang et al., 1993; Yan et al., 2004; Michaelevski et al., 2003). Kv2.1 and Kv2.2 form distinct populations of K+ channels and these subunits are thought to be primarily responsible for IK in superior cervical ganglion cells (Blaine and Ribera, 1998; Burger and Ribera, 1996). -

 

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