Synonyms: GSHPx-1; GPx-1; Cellular glutathione peroxidase; GPX1
Reactivity
Human and Rat
Applications
ELISA, IHC-Frozen, IHC-Paraffin-embedded, WB
Shipment
25°C (ambient)
Long Term Storage
Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial age
Shelf Life
12 months after date of receipt (unopened vial).
Description
Our Anti-Glutathione peroxidase 1 (GPx-1) sheep polyclonal primary antibody detects human and rat Glutathione peroxidase 1 (GPx-1), and is whole serum. It is validated for use in ELISA, IHC-Frozen, IHC-Paraffin-embedded, WB. - Glutathione peroxidase 1 has a role in detoxification of hydrogen peroxide and is one of the most important antioxidant enzymes in humans. It exists as a homotetramer which localises to the cytoplasm. It belongs to the glutathione peroxidase family. Glutathione peroxidase 1 is one of few proteins in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. This protein has a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine repeats. The allele with five alanine repeats is significantly associated with breast cancer risk. Two alternatively spliced isoforms have been identified. -
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).