Amenamevir
CAY-27921-25 25 mg
Data Sheet: 
SDS:
SDS:
CAS
841301-32-4
Formulation
A solid
Purity
≥98%
MW
482,5532
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An antiviral inhibitor of HSV-1 helicase-primase complex activity; inhibits recombinant HSV-1 helicase (IC50 = 0.078 μM); inhibits recombinant HSV-1 primase at ≥0.03 μM; inhibits replication of VZV, HSV-1, and HSV-2 in HEF cells (EC50s = 0.047, 0.036, and 0.028 μM, respectively); not cytotoxic to HEF cells (CC50 = >30 μM); inhibits replication of clinal VZV isolates in HEF cells (EC50s = 0.038-0.10 μM); increases survival of cutaneously HSV-1-infected mice in a zosteriform-spread model of progressive HSV-1 infection (ED50 = 1.9 mg/kg twice per day)
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
