Afobazole (hydrochloride)
CAY-22923-1 1 mg
Data Sheet: 
SDS:
SDS:
CAS
173352-39-1
Formulation
A solid
Purity
≥98%
MW
343,9
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A multi-targeted anxiolytic drug with neuroprotective activities; binds to the sigma-1, melatonin MT1, and MT3 receptors, as well as MAO-A (Kis = 5.9, 160, 0.97, and 3.6 µM, respectively, in a radioligand binding assay); decreases the latency to enter, as well as increases the number of entries into and percentage of time spent in, the open arms of the elevated plus maze, indicating anxiolytic-like activity in passive stress-coping BALB/c, but not active stress-coping C57BL/6, mice at 5 mg/kg; decreases stroke volume and neuronal and oligodendroglial cell death in the brain in a rat model of ischemia induced by MCAO at 0.3 and 3 mg/kg
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
