Adriforant (hydrochloride hydrate)
CAY-43638-25 25 mg
Data Sheet: 
SDS:
SDS:
CAS
2096455-90-0
Formulation
A solid
Purity
≥95%
MW
335,3
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A histamine H4 receptor antagonist (Ki = 6.17 nM); prevents histamine-induced shape change, CD11b protein upregulation, and actin polymerization in isolated human eosinophils (IC50s = 0.65, 4.9, and 1.3 nM, respectively); inhibits histamine-induced calcium influx in primary mouse dorsal root ganglion neurons at 10 µM; decreases ear thickness and reduces basophils, eosinophils, neutrophils, and T cell infiltration in a mouse model of calcipotriol-induced atopic dermatitis at 50 mg/kg per day
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
