Vinci-Biochem Srl
Via Ponte di Bagnolo, 10
50059 Vinci (Firenze) Italy

Tel: +39  0571 568 147 e 0571 568 135

Adaptaquin

  CAY-19720-5 5 mg


Data Sheet:     SDS:    

CAS
385786-48-1  

Formulation
A crystalline solid  

Purity
≥95%  

MW
377,8  

Shipment
-20  

Long Term Storage
-20  

Shelf Life
1460  


Description
 
An inhibitor of HIF-PH2 (IC50 = 2 micromolar); stabilizes HIF-1α protein and induces expression of EPO and VEGF in SH-SY5Y human neuroblastoma cells; protects against glutathione depletion-induced cell death in rat primary cortical neurons (IC50 = 0.25 μM); reduces glutamate-induced cell death in HT-22 cells; increases pellet retrieval in the single-pellet reaching task in a a rat autologous striatal blood infusion model of intracerebral hemmorhage and normalizes preference for ipsilateral turns in a mouse model of striatal hemorrhage at 30 mg/kg
 


 
 
 
 

ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
 
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    Vinci-Biochem Srl
    Via Ponte di Bagnolo, 10
    50059 Vinci (Firenze) Italy
    vb@vincibiochem.it
    Tel:+39 0571 568147
    P. IVA 05706610481
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