
Reactivity
Human
Applications
IHC-P
Source / Host
Rabbit
Immunogen
A synthetic peptide corresponding to human Type I Cytokeratin proteins was used as the immunogen for the Type I Cytokeratin antibody.
Clone
KRTL/7784R
Purity
Protein A/G affinity
Long Term Storage
Aliquot the Type I Cytokeratin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Description
This antibody can detect high molecular weight CK10, CK14, CK15 and CK16 and low molecular weight CK19. It usually used in a cytokeratin cocktail with type II cytokeratin antibody.
The keratins are the typical intermediate filament proteins of epithelia, showing an outstanding degree of molecular diversity. Heteropolymeric filaments are formed by pairing of type I and type II molecules. In humans 54 functional keratin genes exist. They are expressed in highly specific patterns related to the epithelial type and stage of cellular differentiation.
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).