Formulation
A solid
Purity
≥95%
MW
569,04684
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An inhibitor of caspase-1, -4, -5, and -11; inhibits caspase-1, -4, and -5 (IC50s = 0.0467, 1.49, and 0.329, respectively, for the recombinant human enzymes) and cleavage of GSDMD by mouse caspase-11 at 10 µM; inhibits LPS- and ATP- or LPS- and nigericin-induced pyroptosis and IL-1β release in mouse BMDMs
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).