AZ 7371
CAY-19310-5 5 mg
Data Sheet: 
SDS:
SDS:
CAS
1494675-86-3
Formulation
A crystalline solid
Purity
≥98%
MW
355,4
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A non-covalent inhibitor of bacterial DprE1; inhibits wild-type M. smegmatis DprE1 and DprE1C394G (IC50 = 0.01 µM for both) but not DprE1Y321H (IC50 = >10 µM); active against wild-type M. tuberculosis DprE1 (MIC = 1.56 µM) and DprE1C387S or DprE1C387G (MICs = 0.39 and 0.78 µM, respectively) but not DprE1Y314H (MIC = >200 µM); selective for these targets over Gram-positive and Gram-negative bacteria but does inhibit phosphodiesterase 6 (PDE6; IC50 = 4 µM)
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
