AS1517499
CAY-29071-1 1 mg
Data Sheet: 
SDS:
SDS:
CAS
919486-40-1
Formulation
A solid
Purity
≥98%
MW
397,858
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A STAT6 inhibitor (IC50 = 21 nM in a reporter assay); inhibits IL-4-induced Th2 differentiation of mouse spleen T cells (IC50 = 2.3 nM); inhibits bronchial smooth muscle hyperresponsiveness and IL-13 production in ovalbumin-sensitized mice at 10 mg/kg; inhibits STAT6 phosphorylation and TEC hyperplasia and decreases serum levels of T3 and T4 in a mouse model of Graves’ disease at 10 mg/kg per day; inhibits tumor growth and liver metastasis in a murine orthotopic 4T1 mammary carcinoma model at 20 mg/kg twice weekly
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
