CAS
1432660-47-3
Formulation
A crystalline solid
Purity
≥98%
MW
481,5
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A potent, selective inhibitor of mutant IDH2 (IC50 = 23 nM) that inhibits 2-HG formation in human glioblastoma U87 and TF-1 cells expressing IDH2-R140Q (IC50s = 11 and 18 nM, respectively); suppresses cell growth of primary human AML cells and induces differentiation of immature blast cells towards macrophage and granulocytic lineages
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).