CAS
1355326-35-0
Formulation
A crystalline solid
Purity
≥98%
MW
462,6
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
Selective inhibitor of IDH1 R132H and R132C mutants in vitro (IC50s = 0.07 and 0.16 µM, respectively) but not wild-type IDH1, wild-type IDH2, or IDH2 mutants (IC50s > 100 μM); anti-tumor efficacy in vitro and in vivo; induces demethylation of histone H3K9me3 and expression of genes associated with gliogenic differentiation
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).