Synonyms: Tyrphostin AG-555|Tyrphostin B46


CAS
133550-34-2
Formulation
A crystalline solid
Purity
≥95%
MW
322,4
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A tyrphostin EGFR inhibitor (IC50 = 0.7 μM); selectively inhibits EFGR over ErbB2 (IC50 = 35 μM); inhibits EGF-dependent growth of HER 14 cells (IC50 = 2.5 μM) as well as the growth of psoriatic keratinocytes isolated from patients with psoriasis from 1-50 μM; inhibits Mo-MuLV reverse transcriptase activity (IC50 = 10.8 μM) without affecting Mo-MuLV-infected NIH3T3 cell growth (IC50 = 210 μM)
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).