ACTH (1-17) (human, mouse, rat, porcine, bovine, ovine) (tri
CAY-27429-10 10 mg
Synonyms: Adrenocorticotropic Hormone (1-17)|SYSMEHFRWGKPVGKKR-OH
Data Sheet: 
SDS:
SDS:
Formulation
A solid
Purity
≥98%
MW
2093,41546
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A peptide fragment of ACTH; binds to MCRs (Kis = 0.23, 14, 419, and 4,240 nM for MC1R, MC3R, MC4R, and MC5R, respectively); an agonist at MC1R that increases adenylate cyclase activity (EC50 = 3.02 nM in HEK293 cells expressing MC1R); increases MAP following bleeding-induced hypotension in rats 15-30 minutes after i.v. administration; induces melanogenesis in a biphasic manner (EC50s = 0.0001 and 0.08 nM) and differentiation of melanocytes at 0.01-1,000 nM
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
