ABP 688
CAY-30929-5 5 mg
Data Sheet: 
SDS:
SDS:
CAS
924298-51-1
Formulation
A solid
Purity
≥98%
MW
240,30042
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A non-competitive antagonist of mGluR5 (Ki = 3.5 nM in a radioligand binding assay using L(tk-) cell membranes expressing human receptors); binds at an allosteric binding site; selective for mGluR5 receptors over a panel of CNS G protein-coupled receptors, ion channels, and transporters at 10 μM; inhibits quisqualate-induced phosphoinositol accumulation in and glutamate-induced calcium release from L(tk-) cells expressing human mGluR5 (IC50s = 2.4 and 2.3 nM, respectively); radiolabeled forms have been used as PET tracers for in vivo imaging of mGluR5 receptors in rodents
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
