A-804598
CAY-20060-10 10 mg
Data Sheet: 
SDS:
SDS:
CAS
1125758-85-1
Formulation
A crystalline solid
Purity
≥98%
MW
315,4
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A potent and selective competitive antagonist of the P2X7 receptor (IC50s = 9.9 and 10.9 nM in 132N1 cells transfected with the rat or mouse receptor, respectively), inhibits IL-1β release in LPS and IFN-γ-stimulated THP-1 cells (IC50 = 8.5 nM); selective over other P2X and P2Y receptors at concentrations up to 100 µM; prevents footshock-induced increases in IL-1β mRNA in the rat hypothalamus
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
