4'-hydroxy Chalcone
CAY-22898-5 5 g
Synonyms: 2-Benzal-4'-hydroxyacetophenone|2-Benzylidene-4'-hydroxyacetophenone|NSC 242264|p-Cinnamoylphenol
Data Sheet: 
SDS:
SDS:
CAS
2657-25-2
Formulation
A crystalline solid
Purity
≥98%
MW
224,3
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A chalcone metabolite; estrogenic and cytotoxic in MCF-7 cells at concentrations higher than 100 nM; inhibits TNF-α-induced NF-κB signaling and the trypsin-, chymotrypsin-, and caspase-like proteolytic activities of the 26S proteasome in K562 cells in a dose-dependent manner; reduces growth of K562, U937, and Jurkat cancer cell lines in a dose-dependent manner without effecting viability of PBMCs; inhibits GSH-RD (IC50 = 47.3 μM) in vitro in a reversible and non-competitive manner
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
