1A-116
CAY-40781-10 10 mg
Data Sheet: 
SDS:
SDS:
CAS
1430208-73-3
Formulation
A solid
Purity
≥98%
MW
307,3
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An inhibitor of Rac1 (IC50 = 4 µM); reduces the secretion of CXCL5, CXCL10, HGF, CCL2, and MMP-2 from patient-derived AML cells at 20 µM; inhibits the proliferation and migration of, and induces apoptosis in, LN-229 glioblastoma cells at 10 hours, but not 23 hours, post-synchronization at 20 µM; decreases the number of lung nodules and macronodules, as well as total lung weight, in a F3II murine breast cancer model of lung tumor formation at 3 mg/kg per day; inhibits the asexual replication of the P. falciparum strains D10 and W2 (IC50s = 3.21 and 6.89 µM, respectively) and sexual replication in P. falciparum 3D7 immature and mature gametocytes (IC50s = 78.13 and 56.64 µM, respectively)
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
