1-Oleoyl-2-hydroxy-sn-glycero-3-PA (sodium salt)
CAY-62215-10 10 mg
Synonyms: 18:1 LPA|1-Octadecenoyl-2-hydroxy-sn-glycero-3-phosphate|1-Oleoyl LPA|1-Oleoyl Lysophosphatidic Acid|LPA 18:1|PA(18:1/0:0)
Data Sheet: 
SDS:
SDS:
CAS
325465-93-8
Formulation
A crystalline solid
Purity
≥95%
MW
458,5
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
1-Oleoyl-2-hydroxy-sn-glycero-3-PA is a species of LPA containing oleic acid at the sn-1 position. Phosphatidic acid is produced either directly through the action of PLD or through a two step process involving liberation of DAG by PLC followed by phosphorylation of DAG by diglycerol kinase.{2656} Hydrolysis of the fatty acid at the sn-2 position by PLA2 yields bioactive LPA. LPA binds to one of four different G-protein linked receptors{13001} to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.{2656} 1-Oleoyl-2-hydroxy-sn-glycero-3-PA is the most potent of the LPA analogs for calcium mobilization in A431 cells{2665} and for growth stimulation of a variety of cell lines.{2666}
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
