(S)-Pramipexole (hydrochloride)
CAY-11981-50 50 mg
Data Sheet: 
SDS:
SDS:
CAS
104632-25-9
Formulation
A crystalline solid
Purity
≥98%
MW
284,2
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A dopamine D2S, D2L, D3, and D4 receptor agonist (EC50s = 426.58, 338.84, 2.24, and 128.82 nM, respectively, in a [35S]GTPγS binding assay); a partial agonist of α2A-ARs (EC50 = 3,548.13 nM); selective for dopamine D2-4 receptors (Kis = 954.99, 1,698.24, 12.59, 128.82 nM for for D2S, D2L, D3, and D4 receptors, respectively, in a radioligand binding assay) over D1 and D5 receptors (Kis = >10,000 nM for both); prevents MPTP-induced decreases in the number of dopaminergic neurons in the substantia nigra pars compacta in common marmosets at 60 μg/kg per day before, during, and after administration of MPTP
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
