(R)-Cetirizine (hydrochloride)
CAY-23992-250 250 mg
Data Sheet: 
SDS:
SDS:
CAS
130018-87-0
Formulation
A crystalline solid
Purity
≥98%
MW
461,8
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A selective histamine H1 receptor antagonist; the (R)-enantiomer of cetirizine; binds to the H1 receptor with higher affinity than cetirizine (Kis = 3 and 6 nM, respectively) and is highly selective for H1 over M1-M5 receptors; decreases production of RANTES and eotaxin following antigen stimulation in mouse eosinophils in vitro (MEC = 0.05 µM); dose-dependently decreases histamine-induced nasal rubbing and sneezing in mice (0.01-1% solution)
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
