Inflammasome
  
            adipogen

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Vinci-Biochem S.r.l.
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Tel. +39 0571 568 147
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www.vincibiochem.it
contatti
Adipogen: Manufacturer of key Inflammasome Signaling Reagents
   
 
 
 
An inflammasome represents a high molecular weight complex that activates inflammatory caspases and activates cytokines of the IL-1 family (IL-1b, IL-18). Several inflammasomes have been described including the NLRP1 (NALP1) inflammasome, the NLRP3 (NALP3) inflammasome, the IPAF (NLRC4) inflammasome, the NLRP6 (NALP6) inflammasome, the RIG-I inflammasome and the AIM2 (absent in melanoma 2) inflammasome. Inflammasomes can be activated through multiple signals including live bacteria, microbial toxins, xeno-compounds, PAMPs and DAMPs. As IL-1β and other cytokines are key players in the inflammatory response, it is tempting to speculate that IL-1β, inflammatory caspases and inflammasomes play an important role in several diseases. Gout, an autoinflammatory disease characterized by severe joint inflammation, is associated with the deposition of MSU crystals in joints, among other characteristics. As MSU is a potent NLRP3 inflammasome agonist, it is believed that inflammasome-regulated IL-1β exerts a pathogenic role in gout. Furthermore, IL-1β secretion by the NLRP3 inflammasome is triggered by high extracellular glucose in β-cells. Elevated IL-1β is a risk factor for the development of Type 2 Diabetes Mellitus (T2DM) and contributes to insulin resistance. Thus by functioning as a sensor for metabolic stress, the NLRP3 inflammasome likely contributes to the pathogenesis of gout or T2DM, respectively.
 
 

 
Standard Inflammasome Signaling Antibodies
anti-AIM2 (human), mAb (3B10) 100 ug AG-20B-0040-C100 Adipogen data sheet
anti-Asc, pAb (AL177) 100 ug AG-25B-0006-C100 Adipogen data sheet
anti-Asc, pAb (AL177) (preservative free) 100 ug AG-25B-0006PF-C100 Adipogen data sheet
anti-Cardif (human), mAb (Adri-1) 100 ug AG-20B-0004-C100 Adipogen data sheet
anti-MDA5 (human), mAb (Hely-1) 100 ug AG-20B-0013-C100 Adipogen data sheet
anti-Nod1 (human), pAb (AL184) 50 ug AG-25B-0013-C050 Adipogen data sheet
anti-NS3 (HCV), mAb (1B6) 100 ug AG-20B-0001-C100 Adipogen data sheet
anti-NS5B (HCV), mAb (5B-3B1) 100 ug AG-20B-0002-C100 Adipogen data sheet
anti-NS5B (HCV), mAb (blocking) (5B-12B7) 100 ug AG-20B-0003-C100 Adipogen data sheet
anti-Pyrin (human), pAb (AL196) 100 ug AG-25B-0020-C100 Adipogen data sheet
anti-RIG-I, mAb (Alme-1) 100 ug AG-20B-0009-C100 Adipogen data sheet
anti-RIG-I, mAb (Alme-1) (Biotin) 100 ug AG-20B-0009B-C100 Adipogen data sheet
         
         
Other Inflammasome Signaling Antibodies
anti-HMGB1, mAb (rec.) (Giby-1-4) 100 ug AG-27B-0002-C100 Adipogen data sheet
anti-HMGB1, mAb (rec.) (Giby-1-4) (Biotin) 100 ug AG-27B-0002B-C100 Adipogen data sheet
anti-NAIP1/2/5 (mouse), mAb (Naipa-1) 100 ug AG-20B-0045-C100 Adipogen data sheet
anti-NLRP1/NALP1 (human), pAb (AL176) 100 ug AG-25B-0005-C100 Adipogen data sheet
anti-NLRP3/NALP3 (mouse), mAb (Cryo-1) 100 ug AG-20B-0006-C100 Adipogen data sheet
anti-NLRC3 (mouse), mAb (Eowyn-1) 100 µg AG-20B-0067-C100 Adipogen data sheet
anti-NLRP3/NALP3, mAb (Cryo-2) 100 ug AG-20B-0014-C100 Adipogen data sheet
anti-NLRP6/NALP6 (human), mAb (Clint-1) 100 ug AG-20B-0046-C100 Adipogen data sheet
anti-NLRP12/NALP12 (human), pAb (AL236) 100 ug AG-25B-0021-C100 Adipogen data sheet
         
         
Inflammasome Signaling-related Proteins & Antibodies
IL-1beta (human) (rec.) (untagged) 10 ug AG-40B-0023-C010 Adipogen data sheet
IL-1beta (human) (rec.) (untagged) MultiPack 3 x 10 ug AG-40B-0023-3010 Adipogen data sheet
IL-1beta (mouse) (rec.) (untagged) 10 ug AG-40B-0086-C010 Adipogen data sheet
IL-1beta (mouse) (rec.) (untagged) MultiPack 3 x 10 ug AG-40B-0086-3010 Adipogen data sheet
anti-IL-1alpha (mouse), mAb (Bamboo-1) 100 ug AG-20B-0050-C100 Adipogen data sheet
anti-IL-1R2 (mouse), mAb (rec.) (blocking) (Praxy-1-1) 100 ug AG-27B-0011-C100 Adipogen data sheet
IL-1 Receptor Type I (human):Fc (human) (rec.) 50 ug AG-40B-0024-C050 Adipogen data sheet
IL-1 Receptor Type I (human):Fc (human) (rec.) MultiPack 3 x 50 ug AG-40B-0024-3050 Adipogen data sheet
IL-1alpha (human) (rec.) (His) 10 ug CHI-HR-20001A-C010 Chimerigen data sheet
IL-1alpha (human) (rec.) (His) 50 ug CHI-HR-20001A-C050 Chimerigen data sheet
IL-1alpha (mouse) Matched Pair Detection Set 1 Set AG-46B-0004-KI01 Adipogen data sheet
IL-1beta (human) (rec.) (His) 10 ug CHI-HR-20001B-C010 Chimerigen data sheet
IL-1beta (human) (rec.) (His) 50 ug CHI-HR-20001B-C050 Chimerigen data sheet
IL-1alpha (mouse) ELISA Kit 96 wells AG-45B-0003-KI01 Adipogen data sheet
         
         
The Standard Neutrophil Antibody
anti-Neutrophils (mouse), mAb (blocking) (Nimp-R14)  100 ug AG-20B-0043-C100 Adipogen data sheet
anti-Neutrophils (mouse), mAb (blocking) (Nimp-R14) (preservative free) 500 ug AG-20B-0043PF-C500 Adipogen data sheet
anti-Neutrophils (mouse), mAb (blocking) (Nimp-R14) (preservative free) 2 mg AG-20B-0043PF-M002 Adipogen data sheet
anti-Neutrophils (mouse), mAb (blocking) (Nimp-R14) (preservative free) 10 mg AG-20B-0043PF-M010 Adipogen data sheet
         
         
AdipoGen The Manufacturer of High Purity Flagellin
Flagellin 100 ug AG-40B-0095-C100 Adipogen data sheet
Flagellin (high purity) 10 ug AG-40B-0025-C010 Adipogen data sheet
Flagellin (high purity) MultiPack  3 x 10 ug AG-40B-0025-3010 Adipogen data sheet
Flagellin (NLRC4 Mutant) (rec.) 10 ug AG-40B-0126-C010 Adipogen data sheet
Flagellin (NLRC4 Mutant) (rec.) MultiPack 3 x 10 ug AG-40B-0126-3010 Adipogen data sheet
Flagellin (rec.) 10 ug AG-40B-0125-C010 Adipogen data sheet
Flagellin (rec.) MultiPack 3 x 10 ug AG-40B-0125-3010 Adipogen data sheet
Flagellin (TLR5 Mutant) (rec.) 10 ug AG-40B-0127-C010 Adipogen data sheet
Flagellin (TLR5 Mutant) (rec.) MultiPack 3 x 10 ug AG-40B-0127-3010 Adipogen data sheet
         
         
NLRP3/NALP3 Inflammasome Activators
Monosodium urate [MSU] (crystals) 2 mg AG-CR1-3950-M002 Adipogen data sheet
Monosodium urate [MSU] (ready-to-use) 10 mg AG-CR1-3951-M010 Adipogen data sheet
Nigericin . sodium salt 25 mg AG-CN2-0020-M025 Adipogen data sheet
Nigericin . sodium salt 5 mg AG-CN2-0020-M005 Adipogen data sheet
         
         
Inflammasome Priming Activators
Kdo2-Lipid A (ready-to-use) 1 mg AG-CU1-0001-M001 Adipogen data sheet
TNF-alpha (human) (multimeric) (rec.) 10 ug AG-40B-0019-C010 Adipogen data sheet
TNF-alpha, Soluble (human) (rec.) 50 ug AG-40B-0006-C050 Adipogen data sheet
TNF-alpha, Soluble (human) (rec.) 10 ug AG-40B-0006-C010 Adipogen data sheet
TNF-alpha, Soluble (human) (rec.) MultiPack 3 x 50 ug AG-40B-0006-3050 Adipogen data sheet
TNF-R1 (human):Fc (human) (rec.) 50 ug AG-40B-0074-C050 Adipogen data sheet
TNF-R1 (human):Fc (human) (rec.) MultiPack 3 x 50 ug AG-40B-0074-3050 Adipogen data sheet
         
         
Inflammasome Inhibitors
BAY 11-7082 50 mg AG-CR1-0013-M050 Adipogen data sheet
BAY 11-7082 10 mg AG-CR1-0013-M010 Adipogen data sheet
Colchicine 1 g AG-CN2-0048-G001 Adipogen data sheet
Colchicine 500 mg AG-CN2-0048-M500 Adipogen data sheet
         
         
Inflammasome other products
(R)-FSL-1 100 ug AG-CP3-0010-C100 Adipogen data sheet
7BIO 50 mg MR-C0020-M050 ManRos data sheet
7BIO 10 mg MR-C0020-M010 ManRos data sheet
Caspase-1 (mouse) ELISA Kit 96 wells AG-45B-0002-KI01 Adipogen data sheet
Caspase-1 (mouse) Matched Pair Detection Set 1 Set AG-46B-0003-KI01 Adipogen data sheet
anti-Caspase-1 (p10) (mouse), mAb (Casper-2) 100 ug AG-20B-0044-C100 Adipogen data sheet
anti-Caspase-1 (p10) (mouse), mAb (Casper-2) (Biotin) 100 ug AG-20B-0044B-C100 Adipogen data sheet
anti-Caspase-1 (p20) (human), mAb (Bally-1) 100 ug AG-20B-0048-C100 Adipogen data sheet
anti-Caspase-1 (p20) (human), mAb (Bally-1) (Biotin) 100 ug AG-20B-0048B-C100 Adipogen data sheet
anti-Caspase-1 (p20) (mouse), mAb (Casper-1) 100 ug AG-20B-0042-C100 Adipogen data sheet
anti-Caspase-1 (p20) (mouse), mAb (Casper-1) (Biotin) 100 ug AG-20B-0042B-C100 Adipogen data sheet
CD40L (human) (multimeric) (rec.) 10 ug AG-40B-0010-C010 Adipogen data sheet
CD40L (human) (multimeric) (rec.) MultiPack 3 x 10 ug AG-40B-0010-3010 Adipogen data sheet
CD40L (mouse) (multimeric) (rec.) 10 ug AG-40B-0020-C010 Adipogen data sheet
CD40L (mouse) (multimeric) (rec.) MultiPack 3 x 10 ug AG-40B-0020-3010 Adipogen data sheet
CD40L (rat) (multimeric) (rec.) 10 ug AG-40B-0107-C010 Adipogen data sheet
CD40L (rat) (multimeric) (rec.) MultiPack 3 x 10 ug AG-40B-0107-3010 Adipogen data sheet
FSL-1 100 ug AG-CP3-0009-C100 Adipogen data sheet
Gardiquimod 5 mg AG-CR1-3583-M005 Adipogen data sheet
Gardiquimod 25 mg AG-CR1-3583-M025 Adipogen data sheet
IAXO-101 (CD14/TLR4 Antagonist) (synthetic) 5 mg IAX-600-001-M005 Innaxon data sheet
IAXO-101 (CD14/TLR4 Antagonist) (synthetic) 1 mg IAX-600-001-M001 Innaxon data sheet
IAXO-102 (CD14/TLR4 Antagonist) (synthetic) 5 mg IAX-600-002-M005 Innaxon data sheet
IAXO-102 (CD14/TLR4 Antagonist) (synthetic) 1 mg IAX-600-002-M001 Innaxon data sheet
IAXO-103 (CD14/TLR4 Antagonist) (synthetic) 1 mg IAX-600-003-M001 Innaxon data sheet
IAXO-103 (CD14/TLR4 Antagonist) (synthetic) 5 mg IAX-600-003-M005 Innaxon data sheet
IAXO-201 (Control for IAXO-102) (synthetic) 1 mg IAX-600-004-M001 Innaxon data sheet
IAXO-202 (Control for IAXO-101/IAXO-103) (synthetic) 1 mg IAX-600-005-M001 Innaxon data sheet
iODN (inhibitory ODN) 2088 Endotoxin-free (sterile) (includes IAX-900-002-L010) 3 x 1 mg IAX-200-050-3001 Innaxon data sheet
iODN (inhibitory ODN) 2088 Endotoxin-free (sterile) (includes IAX-900-002-L010) 1 mg IAX-200-050-M001 Innaxon data sheet
iODN (inhibitory ODN) 2088 Endotoxin-free (sterile) (includes IAX-900-002-LD15) 100 ug IAX-200-050-C100 Innaxon data sheet
Lipid A from E. coli R515 (Re) TLRpure Powder 5 mg IAX-100-004DF-M005 Innaxon data sheet
Lipid A from E. coli R515 (Re) TLRpure Powder 1 mg IAX-100-004DF-M001 Innaxon data sheet
Lipid A from E. coli R515 (Re) TLRpure Sterile Solution 500 ug IAX-100-004-C500 Innaxon data sheet
Lipid A from E. coli R515 (Re) TLRpure Sterile Solution 1 mg IAX-100-004-M001 Innaxon data sheet
Lipid A from E. coli R515 (Re) TLRpure Sterile Solution  250 ug IAX-100-004-C250 Innaxon data sheet
Lipid A from S. minnesota R595 (Re) TLRpure Powder 5 mg IAX-100-001DF-M005 Innaxon data sheet
Lipid A from S. minnesota R595 (Re) TLRpure Powder 1 mg IAX-100-001DF-M001 Innaxon data sheet
Lipid A from S. minnesota R595 (Re) TLRpure Sterile Solution  1 mg IAX-100-001-M001 Innaxon data sheet
Lipid A from S. minnesota R595 (Re) TLRpure Sterile Solution  500 ug IAX-100-001-C500 Innaxon data sheet
Lipid A from S. minnesota R595 (Re) TLRpure Sterile Solution  250 ug IAX-100-001-C250 Innaxon data sheet
Loxoribine 25 mg AG-CR1-3584-M025 Adipogen data sheet
Loxoribine 5 mg AG-CR1-3584-M005 Adipogen data sheet
LPS (Universal) from S. abortus equi (S-form) TLRpure Sterile Solution  500 ug IAX-100-009-C500 Innaxon data sheet
LPS (Universal) from S. abortus equi (S-form) TLRpure Sterile Solution  1 mg IAX-100-009-M001 Innaxon data sheet
LPS (Universal) from S. abortus equi (S-form) TLRpure Sterile Solution  5 x 1 mg IAX-100-009-5001 Innaxon data sheet
LPS from E. coli EH100 (Ra) TLRpure Sterile Solution 500 ug IAX-100-010-C500 Innaxon data sheet
LPS from E. coli EH100 (Ra) TLRpure Sterile Solution 5 x 1 mg IAX-100-010-5001 Innaxon data sheet
LPS from E. coli EH100 (Ra) TLRpure Sterile Solution 1 mg IAX-100-010-M001 Innaxon data sheet
LPS from E. coli J5 (Rc) TLRpure Sterile Solution 5 x 1 mg IAX-100-014-5001 Innaxon data sheet
LPS from E. coli J5 (Rc) TLRpure Sterile Solution 500 ug IAX-100-014-C500 Innaxon data sheet
LPS from E. coli J5 (Rc) TLRpure Sterile Solution 1 mg IAX-100-014-M001 Innaxon data sheet
LPS from E. coli O111:B4 (S-form) TLRpure Sterile Solution  500 ug IAX-100-012-C500 Innaxon data sheet
LPS from E. coli O111:B4 (S-form) TLRpure Sterile Solution  1 mg IAX-100-012-M001 Innaxon data sheet
LPS from E. coli O111:B4 (S-form) TLRpure Sterile Solution  5 x 1 mg IAX-100-012-5001 Innaxon data sheet
LPS from E. coli O55:B5 (S-form) TLRpure Sterile Solution 500 ug IAX-100-013-C500 Innaxon data sheet
LPS from E. coli O55:B5 (S-form) TLRpure Sterile Solution 5 x 1 mg IAX-100-013-5001 Innaxon data sheet
LPS from E. coli O55:B5 (S-form) TLRpure Sterile Solution 1 mg IAX-100-013-M001 Innaxon data sheet
LPS from E. coli O8:K27 (S-form) TLRpure Sterile Solution 500 ug IAX-100-006-C500 Innaxon data sheet
LPS from E. coli O8:K27 (S-form) TLRpure Sterile Solution 5 x 1 mg IAX-100-006-5001 Innaxon data sheet
LPS from E. coli O8:K27 (S-form) TLRpure Sterile Solution 1 mg IAX-100-006-M001 Innaxon data sheet
LPS from E. coli R515 (Re) TLRpure Sterile Solution 500 ug IAX-100-007-C500 Innaxon data sheet
LPS from E. coli R515 (Re) TLRpure Sterile Solution 1 mg IAX-100-007-M001 Innaxon data sheet
LPS from E. coli R515 (Re) TLRpure Sterile Solution 5 x 1 mg IAX-100-007-5001 Innaxon data sheet
LPS from S. abortus equi (S-form) Biotin TLRpure Sterile Solution 500 ug IAX-100-009B-C500 Innaxon data sheet
LPS from S. abortus equi (S-form) Biotin TLRpure Sterile Solution 250 ug IAX-100-009B-C250 Innaxon data sheet
LPS from S. enteritidis (S-form) TLRpure Sterile Solution 5 x 1 mg IAX-100-019-5001 Innaxon data sheet
LPS from S. enteritidis (S-form) TLRpure Sterile Solution 1 mg IAX-100-019-M001 Innaxon data sheet
LPS from S. enteritidis (S-form) TLRpure Sterile Solution 500 ug IAX-100-019-C500 Innaxon data sheet
LPS from S. minnesota (S-form) TLRpure Sterile Solution  1 mg IAX-100-020-M001 Innaxon data sheet
LPS from S. minnesota (S-form) TLRpure Sterile Solution  500 ug IAX-100-020-C500 Innaxon data sheet
LPS from S. minnesota (S-form) TLRpure Sterile Solution  5 x 1 mg IAX-100-020-5001 Innaxon data sheet
LPS from S. minnesota R3 (Rd2) TLRpure Sterile Solution 1 mg IAX-100-021-M001 Innaxon data sheet
LPS from S. minnesota R3 (Rd2) TLRpure Sterile Solution 500 ug IAX-100-021-C500 Innaxon data sheet
LPS from S. minnesota R3 (Rd2) TLRpure Sterile Solution 5 x 1 mg IAX-100-021-5001 Innaxon data sheet
LPS from S. minnesota R345 (Rb) TLRpure Sterile Solution 1 mg IAX-100-015-M001 Innaxon data sheet
LPS from S. minnesota R345 (Rb) TLRpure Sterile Solution 5 x 1 mg IAX-100-015-5001 Innaxon data sheet
LPS from S. minnesota R345 (Rb) TLRpure Sterile Solution 500 ug IAX-100-015-C500 Innaxon data sheet
LPS from S. minnesota R5 (Rc) TLRpure Sterile Solution 5 x 1 mg IAX-100-017-5001 Innaxon data sheet
LPS from S. minnesota R5 (Rc) TLRpure Sterile Solution 500 ug IAX-100-017-C500 Innaxon data sheet
LPS from S. minnesota R5 (Rc) TLRpure Sterile Solution 1 mg IAX-100-017-M001 Innaxon data sheet
LPS from S. minnesota R595 (Re) TLRpure Sterile Solution 5 x 1 mg IAX-100-008-5001 Innaxon data sheet
LPS from S. minnesota R595 (Re) TLRpure Sterile Solution 1 mg IAX-100-008-M001 Innaxon data sheet
LPS from S. minnesota R595 (Re) TLRpure Sterile Solution 500 ug IAX-100-008-C500 Innaxon data sheet
LPS from S. minnesota R60 (Ra) TLRpure Sterile Solution 500 ug IAX-100-016-C500 Innaxon data sheet
LPS from S. minnesota R60 (Ra) TLRpure Sterile Solution 1 mg IAX-100-016-M001 Innaxon data sheet
LPS from S. minnesota R7 (Rd1) TLRpure Sterile Solution 500 ug IAX-100-018-C500 Innaxon data sheet
LPS from S. minnesota R7 (Rd1) TLRpure Sterile Solution 1 mg IAX-100-018-M001 Innaxon data sheet
LPS from S. minnesota R7 (Rd1) TLRpure Sterile Solution 5 x 1 mg IAX-100-018-5001 Innaxon data sheet
LPS from S. typhimurium (S-form) TLRpure Sterile Solution 5 x 1 mg IAX-100-011-5001 Innaxon data sheet
LPS from S. typhimurium (S-form) TLRpure Sterile Solution 500 ug IAX-100-011-C500 Innaxon data sheet
LPS from S. typhimurium (S-form) TLRpure Sterile Solution 1 mg IAX-100-011-M001 Innaxon data sheet
Monophosphoryl Lipid A [MPLA] from E. coli R515 (Re) TLRpure Powder 1 mg IAX-100-003DF-M001 Innaxon data sheet
Monophosphoryl Lipid A [MPLA] from E. coli R515 (Re) TLRpure Powder 5 mg IAX-100-003DF-M005 Innaxon data sheet
Monophosphoryl Lipid A [MPLA] from E. coli R515 (Re) TLRpure Sterile Solution 1 mg IAX-100-003-M001 Innaxon data sheet
Monophosphoryl Lipid A [MPLA] from E. coli R515 (Re) TLRpure Sterile Solution 250 ug IAX-100-003-C250 Innaxon data sheet
Monophosphoryl Lipid A [MPLA] from E. coli R515 (Re) TLRpure Sterile Solution 500 ug IAX-100-003-C500 Innaxon data sheet
Monophosphoryl Lipid A [MPLA] from S. minnesota R595 (Re) TLRpure Powder 5 mg IAX-100-002DF-M005 Innaxon data sheet
Monophosphoryl Lipid A [MPLA] from S. minnesota R595 (Re) TLRpure Powder 1 mg IAX-100-002DF-M001 Innaxon data sheet
Monophosphoryl Lipid A [MPLA] from S. minnesota R595 (Re) TLRpure Sterile Solution 250 ug IAX-100-002-C250 Innaxon data sheet
Monophosphoryl Lipid A [MPLA] from S. minnesota R595 (Re) TLRpure Sterile Solution 500 ug IAX-100-002-C500 Innaxon data sheet
Monophosphoryl Lipid A [MPLA] from S. minnesota R595 (Re) TLRpure Sterile Solution 1 mg IAX-100-002-M001 Innaxon data sheet
MPLA (synthetic) Sterile Solution 100 ug AG-CU1-0002-C100 Adipogen data sheet
Pam3Cys-Ser-(Lys)4 . trihydrochloride 2 mg AG-CP3-0003-M002 Adipogen data sheet
POP1 (human) (rec.) 10 ug AG-40B-0123-C010 Adipogen data sheet
POP1 (human) (rec.) MultiPack 3 x 10 ug AG-40B-0123-3010 Adipogen data sheet
Q-VD-OPh 5 mg AG-CP3-0006-M005 Adipogen data sheet
Q-VD-OPh 1 mg AG-CP3-0006-M001 Adipogen data sheet
Q-VD-OPh MultiPack 3 x 1 mg AG-CP3-0006-3001 Adipogen data sheet
Q-VE-OPh (Negative Control for Q-VD-OPh) 1 mg AG-CP3-0007-M001 Adipogen data sheet
R-848 25 mg AG-CR1-3582-M025 Adipogen data sheet
R-848 5 mg AG-CR1-3582-M005 Adipogen data sheet
Zmp1 (M. tuberculosis) (rec.) (His) 50 ug AG-40T-0103-C050 Adipogen data sheet
Z-VAD-FMK (Cell permeable) 5 mg AG-CP3-0002-M005 Adipogen data sheet
Z-VAD-FMK (Cell permeable) 1 mg AG-CP3-0002-M001 Adipogen data sheet
Z-VRPR-FMK 500 ug AG-CP3-0008-C500 Adipogen data sheet
Z-VRPR-FMK 1 mg AG-CP3-0008-M001 Adipogen data sheet
 

 
AdipoGen Innate Immunity
Innate ImmunityAdipoGen®
Inflammasomes & TLR Signaling
The innate immune system plays an essential role in the host’s first line of defense against microbial invasion and involves the recognition of PAMPs or DAMPs by pattern recognition receptors (PRRs). Activation of PRRs triggers cell signaling leading to the production of proinflammatory cytokines, chemokines and type 1 interferons, the induction of antimicrobial and inflammatory responses, pyroptotic cell death and the recruitment of phagocytic cells.
 
 
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