DC_AC50
CAY-19283-25 25 mg
Data Sheet: 
SDS:
SDS:
CAS
497061-48-0
Formulation
A crystalline solid
Purity
≥98%
MW
424,3
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
An inhibitor of Atox1 and CCS; binds to purified Atox1 and CCS (Kds = 6.8 and 8.2 μM, respectively); inhibits the interaction between Atox1 and domain 4 of ATP7B in the presence of zinc in a FRET-based assay at 100 μM; increases copper and ROS levels and decreases COX activity and lipid biosynthesis in H1299 cells at 10 μM; inhibits the proliferation of H1299, K562, MDA-MB-231, and 212LN cancer cells, but not PIG1, HDF, HaCaT, or MCF-10A cells, in a concentration-dependent manner; reduces tumor growth in an H1299 mouse xenograft model at 100 mg/kg per day
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).
