Synonyms: [D-Ala6, des-Gly10]GnRH-ethylamide|des-Gly GnRH|pGlu-HWSYALRP-NHEt


CAS
79561-22-1
Formulation
A crystalline solid
Purity
≥98%
MW
1287,42308
Shipment
-20
Long Term Storage
-20
Shelf Life
1460
Description
A peptide agonist of GnRH; binds to GnRHR (Kd = 0.2 nM); decreases GnRH and GnRHR expression in the preoptic area and pMBH, respectively, of ovariectomized estradiol-treated rats at 6 ng, i.c.v., indicating an ultrashort negative feedback loop; induces desensitization in the pituitary and decreases serum estradiol levels and ovarian and uterine weight in neonatal and adult female rats; reduces tumor growth in an HEC-1-B mouse xenograft model at 20, 40, and 80 µg/mg
ESCLUSIVAMENTE PER USO DI RICERCA (RUO) e non per uso terapeutico o diagnostico su uomini o animali. Il prodotto NON è un Dispositivo Medico o un Diagnostico in Vitro.
PRODUCT FOR RESEARCH USE ONLY (RUO) and not for therapeutic or diagnostic use on humans or animals. The product is NOT a Medical Device or an In-Vitro Diagnostic (IVD).