(±)-SKF 81297 (hydrobromide)

  CAY-15067-25 25 mg

Data Sheet:     SDS:    

---

67287-39-2  

A crystalline solid  

≥98%  

370,7  

-20  

-20  

1460  

---

Description

 

(±)-SKF 81297 is a selective agonist of the dopamine D1-like receptor (Ki = 1.9 nM).{24103} It demonstrates comparatively lower binding affinity for the dopamine D2, dopamine D3, serotonin 5-HT2A, and adrenergic α2 receptors (Kis = 1,272, >10,000, 955, and 509 nM, respectively).{24103} Activation of dopamine D1-like receptors by selective agonists such as (±)-SKF 81297 have been implicated in initiating a cascade of signaling events leading to reward-related incentive learning.{24104}

 

---