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VIROLOGY |
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ANTIVIRAL SIGNALING / Enzo Life Sciences
Scarica PDF (1,02 Mb)
Cytoplasmic Sensors: MDA5 [Helicard], ZBP1
[Z-DNA-binding Protein 1; DAI], RIG-I [Retinoic Acid-inducible Gene 1
Protein], LGP2 [Probable ATP-dependent RNA Helicase DHX58], Cardif
[MAVS; VISA; IPS-1]; Endosome Sensors; Downstream Signaling Adapters;
IFN-Related Products; Ligands for Intracellular Sensors: TLR3/7/8, TLR9;
Hepatitis C Virus Reagents; BioProbe® Products: Adenovirus BioProbe®; BK
Virus BioProbe®; Cytomegalovirus BioProbe®; Hepatitis A Virus BioProbe®,
Herpes Simplex Virus BioProbe®, JC Virus BioProbe®, SV40 BioProbe®;
PathoGene® Products: PathoGene® HPV Screening Probe, PathoGene® HPV Type
16/18 Probe, PathoGene® HPV Type 31/33/51 Probe, PathoGene® HPV Type
6/11 Probe, PathoGene® Hrp-AEC Human Papillomavirus In Situ Typing Assay
for Tissue Sections (Types 6/11, 16/18 and 31/33/51), PathoGene® Hrp-DAB
Human Papillomavirus In Situ Typing Assay for Tissue Sections (Types
6/11, 16/18 and 31/33/51), PathoGene® Human Papillomavirus In Situ
Screening Assay for Tissue Sections, PathoGene® Alk Phos-NBT/BCIP Human
Papillomavirus In Situ Typing Assay for Tissue Sections (Types 6/11,
16/18 and 31/33/51); SARS Related Products. |
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ELISA, EIA AND OTHER ASSAY KITS / Selected by
Vinci-Biochem
Scarica
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IMMUNOASSAY Kits
/ Enzo Life Sciences
44 pagine.
Scarica PDF (4,32 Mb)
Cellular Analysis
Immunology & Inflammation
Natural Products & Antibiotics
Obesity & Metabolism
Signal Transduction |
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NOD-LIKE RECEPTORS (NLRs)
/ Enzo Life Sciences
8 pagine. Scarica
PDF
(1,6 Mb)
In mammals, germ-line encoded pattern recognition receptors (PRRs)
detect the presence of pathogens either directly through recognition of
pathogen-associated molecular patterns (PAMPs) or indirectly through
sensing host-derived danger signals (DAMPs). The innate immune system
comprises several classes of PRRs that allow the early detection of
pathogens at the site of infection.
The membrane-bound toll-like receptors (TLRs) detect microbes on the
cell surface and in endosomes. The RIG-1 (retinoic acidinducible gene
I)-like receptors (RLRs; RLHs) and the Nod-like receptors (NLRs;
nucleotide-binding domain leucine-rich repeat containing receptors)
detect microbial components in the cytosol.
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Key TLR LIGANDS AND THEIR RECEPTORS
/ Enzo Life Sciences
12 pagine. Scarica
PDF (1,4 Mb)
In 1996 the Toll protein in Drosophila was discovered to be important
for defense against microbial infection. One year later a human homolog,
now known as Toll-like receptor 4 (TLR4), has been identified through
database searches. To date, 13 mouse and 10 human TLRs have been
identified. TLRs induce signaling pathways which result in a variety of
cellular responses that include the production of interferons (IFNs) and
various cytokines, such as tumor necrosis factor (TNF)-α, interleukin
(IL)-6 and IL-12. The cytoplasmic region of TLRs consists of a Toll/IL-1
receptor (TIR) domain, showing high similarity to that of the IL-1
receptor family. The extracellular region mainly consists of
leucine-rich repeats (LRRs) which are important for the recognition of
PAMPs. |
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HPV In Situ Assays for Tissue Sections
PathoGene® HRP-AEC Human Papillomavirus In Situ Typing Assay for Tissue Sections
(Types 6/11, 16/18 and 31/33/51)
Reagents for tissue preparation and reagents for the in situ hybridization and
detection and typing of HPV DNA using Horseradish Peroxidase-AEC for signal
generation.
Catalog Number 32877 - 20 assays
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AEC Reagent, 1 mL (Aminoethylcarbazole in dimethylformamide)
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Detection Reagent, 30 mL (Streptavidin-biotinylated horseradish peroxidase
in buffered saline and stabilizers and preservative)
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HPV 16/18 Probe Reagent, 1 mL (Mixture of biotin-labeled HPV 16 and HPV
18-specific probes in buffered formamide and hybridization enhancers)
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HPV 6/11 Probe Reagent, 1 mL (Mixture of biotin-labeled HPV 6 and HPV
11-specific probes in buffered formamide and hybridization enhancers)
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Post Hybridization Reagent, 30 mL (Buffered formamide)
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Proteinase K, 2 x 5 mg (Lyophilized powder)
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Wash Buffer Salts, 5 Packets (Each packet yields 1 liter of wash buffer)
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Blue Counterstain, 30 mL (Ready-to-use aqueous-based hematoxylin)
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HPV 16 Probe Control Slide, 2 x 1 Slide (Double-well slides with fixed HPV
16-positive cells)
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HPV 31/33/51 Probe Reagent, 1 mL (Mixture of biotin-labeled HPV 31, HPV 33
and HPV 51-specific probes in buffered formamide and hybridization
enhancers)
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HPV Tissue Control Slide, 1 Slide (Double-well slide with HPV-positive
formalin-fixed paraffin-embedded tissue)
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Pretreated Specimen Slides, 40 Slides (20 single-well plus 20 double-well
slides)
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Quench Reagent, 30 mL (3% H2O2 in buffered NaCl and EDTA)
PathoGene® Alk Phos-NBT/BCIP Human Papillomavirus In Situ Typing Assay for
Tissue Sections (Types 6/11, 16/18 and 31/33/51)
Reagents for tissue preparation and reagents for the in situ hybridization and
detection and typing of HPV DNA using alkaline phosphatase-NBT/BCIP for signal
generation.
Catalog Number 32895 - Unit Size 10 assays
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AP Detection Reagent, 15 mL (Streptavidin-biotinylated alkaline phosphatase
complex in buffered saline with stabilizers and preservative)
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AP Reaction Buffer,
2 x 10
mL (Buffered saline and alkaline phosphatase enhancers)
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BCIP Reagent, 0.4 mL (Bromochloroindolyl phosphate in solvent)
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Counterstain Concentrate, 30 mL (Eosin Y in alcohol)
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HPV 16 Probe Control Slide, 2 x 1 Slide (Double-well slides with fixed HPV
16-positive cells)
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HPV 16/18 Probe Mix, 0.5 mL (Mixture of biotin-labeled HPV 16 and HPV
18-specific probes in buffered formamide and hybridization enhancers)
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HPV 31/33/51 Probe Mix, 0.5 mL (Mixture of biotin-labeled HPV 31, HPV 33 and
HPV 51-specific probes in buffered formamide and hybridization enhancers)
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HPV 6/11 Probe Mix, 0.5 mL (Mixture of biotin-labeled HPV 6 and HPV
11-specific probes in buffered formamide and hybridization enhancers)
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HPV Tissue Control Slide, 1 Slide (Double-well slide with HPV-positive
formalin-fixed paraffin-embedded tissue)
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Hybridization Wash Reagent, 15 mL (Buffered formamide)
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NBT Reagent, 0.4 mL (Nitroblue tetrazolium in solvent)
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Pretreated Specimen Slides,
2 x 10
Slides (10 single-well plus 10 double-well slides)
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Proteinase K, 5 mg (Lyophilized powder)
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SignaSure® Wash Buffer, 4 packets (Each packet yields 1 liter of wash
buffer)
PathoGene® HRP-DAB Human Papillomavirus In Situ Typing
Assay for Tissue Sections (Types 6/11, 16/18 and 31/33/51)
Reagents for tissue preparation and reagents for the in situ hybridization and
detection and typing of HPV DNA using Horseradish Peroxidase-DAB for signal
generation.
Catalog Number 32874 - Unit Size 20 assays
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Blue Counterstain, 30 mL (Ready-to-use aqueous-based hematoxylin)
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Detection Reagent, 30 mL (Streptavidin-biotinylated horseradish peroxidase
in buffered saline and stabilizers and preservative)
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HPV 16/18 Probe Reagent, 1 mL (Mixture of biotin-labeled HPV 16 and HPV
18-specific probes in buffered formamide and hybridization enhancers)
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HPV 6/11 Probe Reagent, 1 mL (Mixture of biotin-labeled HPV 6 and HPV
11-specific probes in buffered formamide and hybridization enhancers)
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Post Hybridization Reagent, 30 mL (Buffered formamide)
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Proteinase K, 2 x 5 mg (Lyophilized powder)
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Substrate Reagent, 5 x 6 mL (Hydrogen peroxide in acetate buffer)
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DAB Reagent, 1 mL (Diaminobenzidine in buffered stabilizers)
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HPV 16 Probe Control Slide, 2 x 1 Slide (Double-well slides with fixed HPV
16-positive cells)
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HPV 31/33/51 Probe Reagent, 1 mL (Mixture of biotin-labeled HPV 31, HPV 33
and HPV 51-specific probes in buffered formamide and hybridization
enhancers)
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HPV Tissue Control Slide, 1 Slide (Double-well slide with HPV-positive
formalin-fixed paraffin-embedded tissue)
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Pretreated Specimen Slides, 40 Slides (20 single-well plus 20 double-well
slides)
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Quench Reagent, 30 mL (3% H2O2 in buffered NaCl and EDTA)
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Wash Buffer Salts, 5 Packets (Each packet yields 1 liter of wash buffer)
PathoGene® Human Papillomavirus In Situ Screening Assay
for Tissue Sections
Includes slides and tissue preparation reagents and reagents for the in situ
hybridization and detection of HPV DNA using alkaline phosphatase-NBT/BCIP for
signal generation. The kit screens for HPV types 6, 11, 16, 18, 31, 33 and 51.
Catalog Number 32879 - Unit Size 20 assays
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AP Detection Reagent, 15 mL (Streptavidin-biotinylated alkaline phosphatase
complex in buffered saline with stabilizers and preservative)
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Counterstain Concentrate, 30 mL (Eosin Y in alcohol)
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AP Reaction Buffer, 4 X 5 mL (Buffered saline and alkaline phosphatase
enhancers)
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BCIP Reagent, 0.4 mL (Bromochloroindolyl phosphate in solvent)
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HPV DNA Probe Mix, 1 mL (Mixture of biotin-labeled HPV 6, HPV 11, HPV 16,
HPV 18, HPV 31, HPV 33 and HPV 51-specific probes in buffered formamide and
hybridization enhancers)
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HPV Hybridization/Staining Control Slide, 2 x 1 Slide (Single-well slide
with a mixture of fixed HPV positive and negative cells)
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HPV Tissue Control Slide, 1 Slide (Double-well slide with HPV-positive
formalin-fixed paraffin-embedded tissue)
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Hybridization Wash Reagent, 15 mL (Buffered formamide)
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NBT Reagent, 0.4 mL (Nitroblue tetrazolium in solvent)
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Pretreated Specimen Slides, 20 Slides (Single-well slides)
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Proteinase K, 5 mg (Lyophilized powder)
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SignaSure® Wash Buffer, 4 packets (Each packet yields 1 liter of wash
buffer)
Product Name: HPV 16 Control Slide
Catalog No: 31877 - Unit Size 1 slide
Two wells of fixed Caski cells containing HPV 16 genomic DNA to be used as a
typing control slide.
Product Name: PathoGene® HPV Screening Probe
Catalog No: 32884 - Unit Size 1.0 ml
The PathoGene® HPV Screening Probe is a mixture of biotin-labeled HPV 6, HPV 11,
HPV 16, HPV 18, HPV 31, HPV 33, and HPV 51-specific probes in buffered formamide
and hybridization enhancers.
Product Name: PathoGene® HPV Type 6/11 Probe
Catalog No: 32885 - Unit Size 1.0 ml
The PathoGene® HPV Type 6/11 Probe is a mixture of biotin-labeled HPV 6 and HPV
11-specific probes in buffered formamide and hybridization enhancers.
Product Name: PathoGene® HPV Type 16/18 Probe
Catalog No: 32886 - Unit Size 1.0 ml
The PathoGene® HPV Type 16/18 Probe is a mixture of biotin-labeled HPV 16 and
HPV 18-specific probes in buffered formamide and hybridization enhancers.
Product Name: PathoGene® HPV Type 31/33/51 Probe
Catalog No: 32887 - Unit Size 1.0 ml
The PathoGene® HPV Type 31/33/51 Probe is a mixture of biotin-labeled HPV 31,
HPV 33, and HPV 51-specific probes in buffered formamide and hybridization
enhancers.
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