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Transglutaminase
Research |
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Assay |
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Transglutaminase Colorimetric Microassay Kit
Convenient simultaneously screening of 96 samples
in 30 minutes.
No leaching out of absorbed substrate, due to use of covalently coupled
Z-Gln-Gly.
Three-step solid phase micro assay.
Transglutaminases (TGases,
R-glutamyl-peptide amine γ-glutamyl-transferases, EC.2.3.2.13) catalyze
the post-translational modification of proteins by the formation of
isopeptide bonds. This occurs either through protein cross-linking via
ε-(γ-glutamyl)lysine bonds or through incorporation of primary amines at
selected peptide-bound glutamine residues. The cross-linked products are
highly resistant to mechanical challenge and proteolytic degradation,
and their accumulation is found in a number of tissues and processes
where such properties are important, including skin, hair, blood
clotting and wound healing. Transglutaminases are involved in numerous
human diseases including neurodegenerative diseases, autoimmune diseases,
cardiac and vascular diseases and cancer.
LIT: Development and evaluation of a modified colorimetric solid-phase
microassay for measuring the activity of cellular and plasma (Factor
XIII) transglutaminases: V. Thomas et al., Biotechnol. Appl. Biochem.
43, 171 (2006) Role of FcR and factor XIIIA in coated platelet
formation: M. Shawn et al., Blood, 106, 4146 (2005) A role for tissue
transglutaminase in α-gliadin peptide cytotoxicity: W. Sakly et al.,
Clin. Exp. Immunol. 146, 550 (2006) |
Kit |
CVL-OPR0001 |
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Antibodies |
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MAb to N-epsilon (gamma-L-Glutamyl)-L-lysine (153-81D4) (Sepharose) |
1 ml |
CVL-OPR0003 |
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MAb to N-epsilon (gamma-L-Glutamyl)-L-lysine (71A3G4) |
100 ul |
CVL-MAB0009 |
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MAb to N-epsilon (gamma-L-Glutamyl)-L-lysine (71A3G4) |
200 ul |
CVL-MAB0009 |
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MAb to N-epsilon (gamma-L-Glutamyl)-L-lysine (81D1C2) |
100 ul |
CVL-MAB0011 |
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MAb to N-epsilon (gamma-L-Glutamyl)-L-lysine (81D1C2) |
200 ul |
CVL-MAB0011 |
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MAb to N-epsilon (gamma-L-Glutamyl)-L-lysine (81D4) |
100 ul |
CVL-MAB0012 |
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MAb to N-epsilon (gamma-L-Glutamyl)-L-lysine (81D4) |
200 ul |
CVL-MAB0012 |
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MAb to N-epsilon-Acetyl-L-lysine (11A1) |
200 ul |
CVL-MAB0019 |
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MAb to NG,NG'-Dimethyl-L-arginine (21C7) |
100 ul |
CVL-MAB0004 |
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MAb to NG,NG'-Dimethyl-L-arginine (21C7) |
200 ul |
CVL-MAB0004 |
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MAb to NG/NG,NG'-Mono/Di-Methyl-L-arginine (7E6) |
100 ul |
CVL-MAB0002 |
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MAb to NG/NG,NG'-Mono/Di-Methyl-L-arginine (7E6) |
200 ul |
CVL-MAB0002 |
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MAb to NG/NG,NG'-Mono/Di-Methyl-L-arginine (Supernatant) (7E6) |
1 ml |
CVL-MAB0003 |
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MAb to NG-Monomethyl-L-arginine (16B11) |
100 ul |
CVL-MAB0005 |
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MAb to NG-Monomethyl-L-arginine (16B11) |
200 ul |
CVL-MAB0005 |
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MAb to NG-Monomethyl-L-arginine (5D1) |
100 ul |
CVL-MAB0007 |
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MAb to NG-Monomethyl-L-arginine (5D1) |
200 ul |
CVL-MAB0007 |
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MAb to NG-Monomethyl-L-arginine (Supernatant) (16B11) |
1 ml |
CVL-MAB0006 |
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MAb to NG-Monomethyl-L-arginine (Supernatant) (5D1) |
1 ml |
CVL-MAB0008 |
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MAb to Transglutaminase (bacterial) (3C7) |
100 ul |
CVL-MAB0031 |
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MAb to Transglutaminase (bacterial) (3C7) |
200 ul |
CVL-MAB0031 |
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MAb to Transglutaminase 2 (7D2) |
100 ul |
CVL-MAB0024 |
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MAb to Transglutaminase 2 (7D2) |
200 ul |
CVL-MAB0024 |
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MAb to Transglutaminase 2 (7D2) |
200 l |
NZY-A004 |
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MAb to Transglutaminase 3 (human) (B5D) |
100 ul |
CVL-MAB0058 |
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MAb to Transglutaminase 3 (human) (B5D) |
200 ul |
CVL-MAB0058 |
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MAb to Transglutaminase 3 (human) (C2D) |
100 ul |
CVL-MAB0057 |
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MAb to Transglutaminase 3 (human) (C2D) |
200 ul |
CVL-MAB0057 |
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MAb to Transglutaminase 3 (human) (H3) |
100 ul |
CVL-MAB0046 |
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MAb to Transglutaminase 3 (human) (H3) |
200 ul |
CVL-MAB0046 |
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PAb to Peptidylarginine Deiminase I (human), from rabbit |
100 ul |
CVL-PAB0043 |
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PAb to Peptidylarginine Deiminase I (human), from rabbit |
200 ul |
CVL-PAB0043 |
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PAb to Peptidylarginine Deiminase I (human), from rabbit (purified) |
25 g |
CVL-PAB0044 |
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PAb to Peptidylarginine Deiminase II |
100 ul |
CVL-PAB0197 |
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PAb to Peptidylarginine Deiminase II |
200 ul |
CVL-PAB0197 |
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PAb to Peptidylarginine Deiminase III |
100 ul |
CVL-PAB0198 |
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PAb to Peptidylarginine Deiminase III |
200 ul |
CVL-PAB0198 |
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PAb to Peptidylarginine Deiminase IV |
100 ul |
CVL-PAB0199 |
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PAb to Peptidylarginine Deiminase IV |
200 ul |
CVL-PAB0199 |
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PAb to Peptidylarginine Deiminases (human), from rabbit |
100 ul |
CVL-PAB0041 |
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PAb to Peptidylarginine Deiminases (human), from rabbit |
200 ul |
CVL-PAB0041 |
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PAb to Peptidylarginine Deiminases (human), from rabbit (purified) |
25 g |
CVL-PAB0042 |
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PAb to Spermidine, from rabbit |
200 ul |
CVL-PAB0023 |
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PAb to Spermine, from rabbit |
200 ul |
CVL-PAB0022 |
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PAb to Transglutaminase (bacterial) |
100 l |
NZY-A002 |
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PAb to Transglutaminase 1 (human), from rabbit |
100 ul |
CVL-PAB0060 |
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PAb to Transglutaminase 1 (human), from rabbit |
200 ul |
CVL-PAB0060 |
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PAb to Transglutaminase 1 (human), from rabbit (purified) |
25 g |
CVL-PAB0061 |
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PAb to Transglutaminase 2 (human), from rabbit |
100 ul |
CVL-PAB0062 |
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PAb to Transglutaminase 2 (human), from rabbit |
200 ul |
CVL-PAB0062 |
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PAb to Transglutaminase 2 (human), from rabbit (purified) |
25 g |
CVL-PAB0063 |
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PAb to Transglutaminase 2 (human) |
200 l |
NZY-A003 |
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PAb to Transglutaminase 3 (human), from rabbit |
100 ul |
CVL-PAB0064 |
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PAb to Transglutaminase 3 (human), from rabbit |
200 ul |
CVL-PAB0064 |
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PAb to Transglutaminase 3 (human), from rabbit (purified) |
25 g |
CVL-PAB0065 |
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PAb to Transglutaminase 4 (human), from rabbit |
100 ul |
CVL-PAB0066 |
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PAb to Transglutaminase 4 (human), from rabbit |
200 ul |
CVL-PAB0066 |
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PAb to Transglutaminase 4 (human), from rabbit (purified) |
25 g |
CVL-PAB0067 |
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PAb to Transglutaminase 5 (human), from rabbit |
100 ul |
CVL-PAB0068 |
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PAb to Transglutaminase 5 (human), from rabbit |
200 ul |
CVL-PAB0068 |
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PAb to Transglutaminase 5 (human), from rabbit (purified) |
25 g |
CVL-PAB0069 |
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PAb to Transglutaminase 7 (human), from rabbit |
100 ul |
CVL-PAB0070 |
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PAb to Transglutaminase 7 (human), from rabbit |
200 ul |
CVL-PAB0070 |
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PAb to Transglutaminases, from rabbit |
100 ul |
CVL-PAB0024 |
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PAb to Transglutaminases, from rabbit |
200 ul |
CVL-PAB0024 |
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Substances |
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1,3-Dimethyl-2-[(2-oxo-propyl)thio]imidazolium . chloride |
100 mg |
NZY-D003 |
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N-(2,4-Dinitrophenyl)cadaverine . hydrochloride |
100 mg |
NZY-D002 |
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Dansyl-Ahx-Gln-Gln-Ile-Val-OH |
25 mg |
NZY-D001 |
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Biotinyl-cadaverine . hydrochloride |
25 mg |
NZY-B002 |
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Biotin-X-cadaverine . trifluoroacetate |
10 mg |
CVL-OPR0007 |
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Boc-DON-Gln-Ile-Val-OMe |
10 mg |
NZY-B003 |
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Z-Gln-Gly-C-DNS |
25 mg |
NZY-C002 |
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Biotinyl-Thr-Val-Gln-Gln-Glu-Leu-OH |
5 mg |
NZY-B001 |
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Z-Gln-Gly-OH |
1 g |
NZY-C001 |
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N-(Tetramethylrhodaminyl)cadaverine . hydrochloride |
10 mg |
NZY-R001 |
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1,3,4,5-Tetramethyl-2-[(2-oxo-propyl)thio]imidazolium . chloride |
10 mg |
NZY-T101 |
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Calyculin A |
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LKT-C0346 |
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Mant-GDP |
150 units |
JBS-NU-204S |
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DL-α-Difluoromethylornithine . hydrochloride . monohydrate |
10 mg |
ALX-270-283 |
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J-8 . hydrochloride |
5 mg |
ALX-270-208 |
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Proteins |
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Transglutaminase 2 Assay Substance |
10 mg |
NZY-A102 |
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Keratinocyte Transglutaminase (human) (recombinant) (His) |
150 g |
NZY-T009 |
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Transglutaminase 2 (human) (recombinant) (His) |
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NZY-T002 |
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Transglutaminase (guinea pig liver) |
10 U |
NZY-T006 |
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Epidermal Transglutaminase (human) (recombinant) (His) |
200 g |
NZY-T012 |
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Involucrin (human) (recombinant) |
500 g |
NZY-I001 |
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Elafin (human) (recombinant) |
100 g |
ALX-201-240 |
