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The PARP Family
& ADP Ribosylation |
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12
pagine. Scarica
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PARP
Family Proteins & Related Products / XRCC1 / PARP Family Antibodies &
Related Products / The Widest Panel of PARP Inhibitors: PARP Inhibitors / PARG
Inhibitor / PARP Activator / Sirtuins / Antibodies / Inhibitors / NAD+
Metabolism / ADP-Ribosylation / Highly Pure & Fully Active NAD Kinases /
NAD-dependent ADP-ribosylation / Mono-ADP-ribosyltransferases (ARTs; mARTs) /
ART Proteins / ART Antibodies / ADP-ribosylhydrolases (ARHs) / ARH Proteins
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Prodotti: |
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Chemiluminescent PARP1 Assay Kit
BPS-80551 100 reactions
DESCRIPTION: The PARP1 Chemiluminescent Activity Assay kit is designed
to measure PARP1 activity using purified PARP1 or cell extracts
containing PARP1. PARP1 is known to catalyze the NAD-dependent addition
of poly(ADP-ribose) to histones. The PARP1 assay kit comes in a
convenient 96-well format, with purified PARP1 enzyme, histone mixture,
activated DNA, and PARP1 assay buffer for 100 enzyme reactions. The key
to the PARP1 Chemiluminescent Activity Assay is the biotinylated
substrate. With this kit, only three simple steps are required for PARP1
reactions. First, histone proteins are coated on a 96-well plate. Next,
the PARP1 biotinylated substrate is incubated with an assay buffer that
contains the PARP1 enzyme. Finally, the plate is treated with
streptavidin-HRP followed by addition of the HRP substrate to produce
chemiluminescence that can then be measured using a chemiluminescence
reader
APPLICATIONS: Great for studying enzyme kinetics and screening small
molecular inhibitors for drug discovery and HTS applications.
STABILITY: Up to 1 year when stored as recommended.
REFERENCE: Brown JA, Marala RB. J. Pharmacol. Toxicol. Methods 2002
47:137-41. |
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Chemiluminescent PARP2 Assay Kit
BPS-80552 100 reactions
DESCRIPTION: The PARP2 Chemiluminescent Activity Assay kit is designed
to measure PARP2 activity using purified PARP2 or cell extracts
containing PARP2. PARP2 is known to catalyze the NAD-dependent addition
of poly(ADP-ribose) to histones. The PARP2 assay kit comes in a
convenient 96-well format, with purified PARP2 enzyme, histone mixture,
activated DNA, and PARP2 assay buffer for 100 enzyme reactions. The key
to the PARP2 Chemiluminescent Activity Assay is the biotinylated
substrate. With this kit, only three simple steps are required for PARP2
reactions. First, histone proteins are coated on a 96-well plate. Next,
the PARP2 biotinylated substrate is incubated with an assay buffer that
contains the PARP2 enzyme. Finally, the plate is treated with
streptavidin-HRP followed by addition of the HRP substrate to produce
chemiluminescence that can then be measured using a chemiluminescence
reader.
APPLICATIONS: Great for studying enzyme kinetics and screening small
molecular inhibitors for drug discovery and HTS applications.
STABILITY: Up to 1 year when stored as recommended.
REFERENCE: Brown JA, Marala RB. J. Pharmacol. Toxicol. Methods 2002
47:137-41. |
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Chemiluminescent PARP3 Assay Kit
BPS-80553 100 reactions
DESCRIPTION: The PARP3 Chemiluminescent Activity Assay kit is designed
to measure PARP3 activity using purified PARP3 or cell extracts
containing PARP3. PARP3 is known to catalyze the NAD-dependent addition
of poly(ADP-ribose) to histones. The PARP3 assay kit comes in a
convenient 96-well format, with purified PARP3 enzyme, histone mixture,
activated DNA, and PARP assay buffer for 100 enzyme reactions. The key
to the PARP3 Chemiluminescent Activity Assay is the biotinylated
substrate. With this kit, only three simple steps are required for PARP3
reactions. First, histone proteins are coated on a 96-well plate. Next,
the PARP biotinylated substrate is incubated with an assay buffer that
contains the PARP3 enzyme. Finally, the plates are treated with
streptavidin-HRP followed by addition of the HRP substrate to produce
chemiluminescence that can then be measured using a chemiluminescence
reader.
APPLICATIONS: Great for studying enzyme kinetics and screening small
molecular inhibitors for drug discovery and HTS applications.
STABILITY: Up to 1 year when stored as recommended.
REFERENCE: Brown JA, Marala RB. J. Pharmacol. Toxicol. Methods 2002
47:137-41. |
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Chemiluminescent PARP6 Assay Kit
BPS-80556 100 reactions
DESCRIPTION: The PARP6 Chemiluminescent Activity Assay kit is designed
to measure PARP6 activity using purified PARP6 or cell extracts
containing PARP6. PARP6 is known to catalyze the NAD-dependent addition
of poly(ADP-ribose) to histones. The PARP6 assay kit comes in a
convenient 96-well format, with purified PARP6 enzyme, histone mixture,
activated DNA, and PARP assay buffer for 100 enzyme reactions. The key
to the PARP6 Chemiluminescent Activity Assay is the biotinylated
substrate. With this kit, only three simple steps are required for PARP6
reactions. First, histone proteins are coated on a 96-well plate. Next,
the PARP biotinylated substrate is incubated with an assay buffer that
contains the PARP6 enzyme. Finally, the plates are treated with
streptavidin-HRP followed by addition of the HRP substrate to produce
chemiluminescence that can then be measured using a chemiluminescence
reader.
APPLICATIONS: Great for studying enzyme kinetics and screening small
molecular inhibitors for drug discovery and HTS applications.
STABILITY: Up to 1 year when stored as recommended.
REFERENCE: Brown JA, Marala RB. J. Pharmacol. Toxicol. Methods 2002
47:137-41. |
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PARP Cleavage Western Blotting Kit
BML-SK003-0001 1 Kit |
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UPF1035
ALX-270-498
PARP-2 specific inhibitor with 60-fold selectivity for PARP-2 |
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UPF1069
ALX-270-499
PARP-2 specific inhibitor with 26.7-fold selectivity for PARP-2 |
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[K20-monomethyl]Histone H4, mAb (5E10-D8), Mouse
IgG1kappa
ALX-804-674 |
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[K20-trimethyl]Histone H4, mAb (4H1-G3), Mouse
IgG1kappa
ALX-804-675 |
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[K20-trimethyl]Histone
H4, mAb (6F8-D9), Mouse IgG1kappa
ALX-804-676
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Poly(ADP-ribose) polymerase, mAb (C-2-10) (affinity
purified)
BML-SA249-0100 100 g |
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4-Amino-1,8-naphthalimide
BML-AP101-0020 20 mg
BML-AP101-0100 100 mg |
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1,5-Isoquinolinediol
BML-AP102-0020 20 mg
BML-AP102-0100 100 mg |
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Bongkrekic acid
BML-CM113-0100 100 g
BML-CM113-1000 1 mg |
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Poly(ADP-ribose) Immunoblotting Standard
BML-SW100-0025 25 g |
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PARP Immunoblotting Standard (bovine) (purified)
BML-SW111-0100 100 l |
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Poly(ADP-ribose), mAb
BML-SA216-0100 100 l |
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Poly(ADP-ribose) polymerase, mAb (C-2-10) (affinity
purified)
BML-SA249-0100 100 g |
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Poly(ADP-ribose) polymerase, mAb (C-2-10)
BML-SA250-0050 50 l |
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Poly(ADP-ribose) polymerase, pAb
BML-SA253-0025 25 l
BML-SA253-0100 100 l |
