1.  

APOPTRAK [DRAQ5NO]

A new compound with the property to consistently stain viable cells at a low level but with greater up-take upon membrane disruption associated with cell death. APOPTRAK is a N-oxide modification of the cell permeable DNA probe DRAQ5. Compared to DRAQ5, APOPTRAK shows reduced cellular penetration properties, but retains the advantageous chromophore and fluorescence characteristics of DRAQ5: Emission wavelengths extending from 665nm to beyond 780nm (Em λ max of 700.5nm for 647nm excitation) permit the use of APOPTRAK staining alone or its incorporation into existing fluorometric protocols for live/dead cell discrimination using visible range fluorochromes or GFP-based probes. Importantly in contrast to propidium iodide APOPTRAK will positively label intact cells at a low level (providing a positive discrimination/reference signal while compromised membranes/cellular integrity will result in a significantly increased signal).

2.  

Antibodies Conjugated to ATTO DYES  

Advantages of ATTO Dyes: Increased Photostability, Outstanding Brightness, High Thermal Stability, Intense Signals (emax > 90,000), Resistant to Environmental Changes, Insignificant Isomerization.

ATTO 488: Alternative to Alexa Fluor 488 Outperforms FITC, R-PE, and Cy2

ATTO 590: Alternative to Texas Red and Alexa Fluor 594

ATTO 647N: shows red fluorescence (λabs (max): 645nm, λem (max): 669nm, εmax: 120000).  

3.  

CE Dye Kits: capillary electrophoresis made easy  

4.  

Chromeo Dyes  

Chromeo 488, Chromeo 494, Chromeo 546 and Chromeo 642 exhibit superior luminescence properties, broad Stokes shifts, stability towards photobleaching and pH, and low cell toxicity. In addition, they are compatible with most excitation sources including diode lasers, LEDs, tungsten lamps and xenon arc lamps. Chromeo Dyes are typically used to label biomolecules covalently in a chemical reaction. The Chromeo Dyes are available in different formats. As amine reactive NHS-Esters are useful to label amino groups in peptides, proteins or amino modified DNA. Secondary antibodies are available.

5.  

CyGEL  

CyGEL is a novel thermoreversible mounting medium for LIVE cells. It can be used as a convenient mounting medium to immobilise non-adherent cells and beads. CyGEL is unusual in that it is a liquid when cold and a gel when warmed!  Key Features: Compatible with LIVE cells, Optically clear with low autofluorescence, Controllable and rapid transition from liquid to gel, Convenient immobilisation of non-adherent cells and beads, Compatible with GFP and "in gel" fluorescent probes including DRAQ5 (Prod. No. BOS-889-001). Advantages: Allows rapid preparation of cells for gel mounting, Permits long term analysis of non-adherent cells, Acts as a support matrix for cells, tissues and beads, Permits sterile, low temperature recovery of cells from gel, Multiple assay formats and applications including apoptosis detection.  

6.  

CyTRAK Orange  

CyTRAK Orange (Prod. No. BOS-889-004) is a novel orange fluorescent dye (related to DRAQ5 (Prod. No. BOS-889-001)) that stains both nucleus and cytoplasm. It is water soluble and membrane permeant and can be used in LIVE cells in combination with other common fluorophores, especially GFP fusions, FITC-labelled antibodies and far-red dyes.  CyTRAK Orange (Prod. No. BOS-889-004) can be used as a LIVE cell nuclear stain or as a cell location dye to define the perimeter of the cell in a variety of cell-based assays. It is highly compatible with existing protocols and can be used across a wide range of instrumentation platforms.  Applications: Real-time Live Cell Imaging ; Cell-based HCS Assays ; Fixed Cell Assays/Imaging/FISH  

7.  

DRAQ5

A cell-permeant far red-fluorescing DNA probe. DRAQ5 is a highly cell permeable DNA-interactive agent, with fluorescence signature extending into the infrared region of the spectrum. The unique characteristics of DRAQ5 offer exciting new advantages for investigations using both fixed specimens and viable cells.  

8.  

LavaCell

LavaCell rapidly stains cellular membranes in live or fixed cells.  

9.  

LigandLink  

Universal Labeling technology provides a small ligand that can carry a variety of functional tags, including fluorescent dyes. Expression of your protein of interest as a LigandLink fusion enables you to specifically label the protein in vivo simply by adding one of the LigandLink Labels to the medium. To change the properties of your tag, all you need to do is add a different LigandLink Label. This means that it is now possible to create a single protein fusion that can be labeled with a variety of tags, depending on the needs of your experiment.  

10.  

ProStain Protein Quantification Kit  

It simplifies the determination of cell extract protein concentrations by providing highly sensitive detection reagents that are easy to use.  

11.  

ToxCount  

ToxCount is a convenient, accurate cell viability assay

Active Motif's ToxCount Cell Viability Assay provides reagents to perform a simple two-color fluorescence cell viability assay. The ToxCount assay is based on the simultaneous determination of live and dead cells with two probes, calcein AM and ethidium homodimer (EthD-1), that recognize parameters of cell viability including intracellular esterase activity and plasma membrane integrity, respectively.